BMP2 antibody (AA 283-396)

Catalog No. ABIN513751

Product Details anti-BMP2 Antibody

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Binding Specificity: AA 283-396

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant BMP2.

Sequence: QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BMP2 (NP_001191, 283 a.a. ~ 396 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3G7

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-BMP2 antibody (ABIN513751)

Ansari, Phark, Duarte, Paulino da Silva, Sharifzadeh, Moshaverinia, Zadeh: "Biomechanical analysis of engineered bone with anti-BMP2 antibody immobilized on different scaffolds." in: Journal of biomedical materials research. Part B, Applied biomaterials, (2015) (PubMed).

Ansari, Freire, Pang, Abdelhamid, Almohaimeed, Zadeh: "Immobilization of murine anti-BMP-2 monoclonal antibody on various biomaterials for bone tissue engineering." in: BioMed research international, Vol. 2014, pp. 940860, (2014) (PubMed).

Freire, Kim, Kook, Nguyen, Zadeh: "Antibody-mediated osseous regeneration: the early events in the healing response." in: Tissue engineering. Part A, Vol. 19, Issue 9-10, pp. 1165-74, (2013) (PubMed).

Moshaverinia, Ansari, Chen, Xu, Akiyama, Snead, Zadeh, Shi: "Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering." in: Biomaterials, Vol. 34, Issue 28, pp. 6572-9, (2013) (PubMed).

Ansari, Moshaverinia, Pi, Han, Abdelhamid, Zadeh: "Functionalization of scaffolds with chimeric anti-BMP-2 monoclonal antibodies for osseous regeneration." in: Biomaterials, Vol. 34, Issue 38, pp. 10191-8, (2013) (PubMed).

Freire, You, Kook, Choi, Zadeh: "Antibody-mediated osseous regeneration: a novel strategy for bioengineering bone by immobilized anti-bone morphogenetic protein-2 antibodies." in: Tissue engineering. Part A, Vol. 17, Issue 23-24, pp. 2911-8, (2011) (PubMed).

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP2 (BMP2 Products)

Background: Full Gene Name: bone morphogenetic protein 2
Synonyms: BMP2A

Gene ID: 650

NCBI Accession: NM_001200

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation