AKT2 antibody (AA 100-189)

Catalog No. ABIN513224

Product Details anti-AKT2 Antibody

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Binding Specificity: AA 100-189

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AKT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against a partial recombinant AKT2.

Sequence: MRAIQMVANS LKQRAPGEDP MDYKCGSPSD SSTTEEMEVA VSKARAKVTM NDFDYLKLLG KGTFGKVILV REKATGRYYA MKILRKEVII

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AKT2 (AAA58364, 100 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1D9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKT2 antibody (ABIN513224)

Lincová, Hampl, Pernicová, Starsíchová, Krcmár, Machala, Kozubík, Soucek: "Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs." in: Biochemical pharmacology, Vol. 78, Issue 6, pp. 561-72, (2009) (PubMed).

Target Details for AKT2

Target: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Alternative Name: AKT2 (AKT2 Products)

Background: Full Gene Name: v-akt murine thymoma viral oncogene homolog 2
Synonyms: PKBB,PKBBETA,PRKBB,RAC-BETA

Gene ID: 208

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling