AHCY antibody (AA 1-432)

Catalog No. ABIN513196

Product Details anti-AHCY Antibody

Target: AHCY (Adenosylhomocysteinase (AHCY))

Binding Specificity: AA 1-432

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AHCY antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a full length recombinant AHCY.

Sequence: MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYS ASKPLKGARI AGCLHMTVET AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVY AWKGETDEEY LWCIEQTLYF KDGPLNMILD DGGDLTNLIH TKHPQLLPGI RGISEETTTG VHNLYKMMAN GILKVPAINV NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFGARVI ITEIDPINAL QAAMEGYEVT TMDEACQEGN IFVTTTGCID IILGRHFEQM KDDAIVCNIG HFDVEIDVKW LNENAVEKVN IKPQVDRYRL KNGRRIILLA EGRLVNLGCA MGHPSFVMSN SFTNQVMAQI ELWTHPDKYP VGVHFLPKKL DEAVAEAHLG KLNVKLTKLT EKQAQYLGMS CDGPFKPDHY RY

Cross-Reactivity: Human

Immunogen: AHCY (AAH11606, 1 a.a. ~ 432 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4H2

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites fluid

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AHCY antibody (ABIN513196)

Chayka, DAcunto, Middleton, Arab, Sala: "Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells." in: The Journal of biological chemistry, Vol. 290, Issue 4, pp. 2198-212, (2015) (PubMed).

Fernandez-Sanchez, Gonatopoulos-Pournatzis, Preston, Lawlor, Cowling: "S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation." in: Molecular and cellular biology, Vol. 29, Issue 23, pp. 6182-91, (2009) (PubMed).

Target Details for AHCY

Target: AHCY (Adenosylhomocysteinase (AHCY))

Alternative Name: AHCY (AHCY Products)

Background: Full Gene Name: S-adenosylhomocysteine hydrolase
Synonyms: SAHH

Gene ID: 191