beta 2 Adrenergic Receptor antibody (AA 1-413)

Catalog No. ABIN513155

Product Details anti-beta 2 Adrenergic Receptor Antibody

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Binding Specificity: AA 1-413

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This beta 2 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Mouse polyclonal antibody raised against a full-length human ADRB2 protein.

Sequence: MGQPGNGSAF LLAPNRSHAP DHDVTQQRDE VWVVGMGIVM SLIVLAIVFG NVLVITAIAK FERLQTVTNY FITSLACADL VMGLAVVPFG AAHILMKMWT FGNFWCEFWT SIDVLCVTAS IETLCVIAVD RYFAITSPFK YQSLLTKNKA RVIILMVWIV SGLTSFLPIQ MHWYRATHQE AINCYANETC CDFFTNQAYA IASSIVSFYV PLVIMVFVYS RVFQEAKRQL QKIDKSEGRF HVQNLSQVEQ DGRTGHGLRR SSKFCLKEHK ALKTLGIIMG TFTLCWLPFF IVNIVHVIQD NLIRKEVYIL LNWIGYVNSG FNPLIYCRSP DFRIAFQELL CLRRSSLKAY GNGYSSNGNT GEQSGYHVEQ EKENKLLCED LPGTEDFVGH QGTVPSDNID SQGRNCSTND SLL

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: ADRB2 (NP_000015, 1 a.a. ~ 413 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-beta 2 Adrenergic Receptor antibody (ABIN513155)

Hudson, Kelly: "Identification of novel competing ?2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells." in: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, Vol. 28, Issue 1, pp. 17-25, (2012) (PubMed).

Lencesova, Sirova, Csaderova, Laukova, Sulova, Kvetnansky, Krizanova: "Changes and role of adrenoceptors in PC12 cells after phenylephrine administration and apoptosis induction." in: Neurochemistry international, Vol. 57, Issue 8, pp. 884-92, (2010) (PubMed).

Target Details for beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Alternative Name: ADRB2 (ADRB2 Products)

Background: Full Gene Name: adrenergic, beta-2-, receptor, surface
Synonyms: ADRB2R,ADRBR,B2AR,BAR,BETA2AR

Gene ID: 154

NCBI Accession: NM_000024

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation