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AADAC antibody (AA 201-300)

AADAC Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2E8 unconjugated
Catalog No. ABIN513029
  • Target See all AADAC Antibodies
    AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))
    Binding Specificity
    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 25
    • 18
    • 17
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 39
    • 1
    Mouse
    Clonality
    • 40
    Monoclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AADAC antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant AADAC.
    Sequence
    QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    AADAC (NP_001077, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2E8
    Isotype
    IgG2b
    Top Product
    Discover our top product AADAC Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Muta, Fukami, Nakajima, Yokoi: "N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity." in: Biochemical pharmacology, Vol. 87, Issue 2, pp. 352-9, (2014) (PubMed).

    Kobayashi, Fukami, Nakajima, Watanabe, Nakajima, Yokoi: "Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 4, pp. 671-9, (2012) (PubMed).

    Shimizu, Fukami, Kobayashi, Takamiya, Aoki, Nakajima, Yokoi: "A novel polymorphic allele of human arylacetamide deacetylase leads to decreased enzyme activity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 6, pp. 1183-90, (2012) (PubMed).

    Kobayashi, Fukami, Higuchi, Nakajima, Yokoi: "Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia." in: Biochemical pharmacology, Vol. 84, Issue 9, pp. 1196-206, (2012) (PubMed).

    Watanabe, Fukami, Nakajima, Takamiya, Aoki, Yokoi: "Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 7, pp. 1513-20, (2009) (PubMed).

  • Target
    AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))
    Alternative Name
    AADAC (AADAC Products)
    Synonyms
    MGC89272 antibody, AADAC antibody, CES5A1 antibody, DAC antibody, Aada antibody, 5033417E09Rik antibody, AI265437 antibody, arylacetamide deacetylase antibody, arylacetamide deacetylase S homeolog antibody, Arylacetamide deacetylase antibody, arylacetamide deacetylase (esterase) antibody, LOC100056411 antibody, aadac antibody, AADAC antibody, aadac.S antibody, LOC100451808 antibody, ACD3 antibody, PTRG_10278 antibody, aaad antibody, Aadac antibody
    Background
    Full Gene Name: arylacetamide deacetylase (esterase)
    Synonyms: CES5A1,DAC
    Gene ID
    13
    NCBI Accession
    NM_001086
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