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HLA-ABC antibody

GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 unconjugated
Catalog No. ABIN5067844
  • Target See all HLA-ABC Antibodies
    HLA-ABC
    Reactivity
    • 67
    • 23
    • 14
    • 13
    • 12
    • 11
    • 11
    • 10
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Human, Baboon, Cynomolgus, Rhesus Monkey
    Host
    • 55
    • 9
    • 3
    Mouse
    Clonality
    • 57
    • 9
    Monoclonal
    Conjugate
    • 28
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-ABC antibody is un-conjugated
    Application
    • 52
    • 16
    • 16
    • 12
    • 11
    • 9
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Anti-HLA-ABC Unconjugated Antibody
    Characteristics
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Human Leukocytes
    Clone
    W6-32
    Isotype
    IgG2a, kappa
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    HLA-ABC
    Alternative Name
    HLA-ABC (HLA-ABC Products)
    Synonyms
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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