HLA-ABC antibody
-
- Target See all HLA-ABC Antibodies
- HLA-ABC
-
Reactivity
- Human, Baboon, Cynomolgus, Rhesus Monkey
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This HLA-ABC antibody is un-conjugated
-
Application
- Flow Cytometry (FACS)
- Purpose
- Anti-HLA-ABC Unconjugated Antibody
- Characteristics
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- Human Leukocytes
- Clone
- W6-32
- Isotype
- IgG2a, kappa
- Top Product
- Discover our top product HLA-ABC Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
-
- Target
- HLA-ABC
- Alternative Name
- HLA-ABC (HLA-ABC Products)
- Synonyms
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
-