CD16 antibody (FITC)

Catalog No. ABIN5067738

Product Details anti-CD16 Antibody (FITC)

Target: CD16

Reactivity: Human, Rhesus Monkey, Baboon, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purpose: CD16 FITC Antibody

Characteristics: The clone 3G8, a mouse monoclonal antibody, binds to the 50-65 kDa transmembrane protein of IgG FcγRIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. 3G8 binds either with the aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human peripheral blood T lymphocytes

Clone: 3G8

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD16

Target: CD16

Alternative Name: CD16 (CD16 Products)

UniProt: Q92835

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process