GDNF antibody (Biotin)
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- Target See all GDNF Antibodies
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GDNF antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.,Detects ~24 kDa.
- Cross-Reactivity
- Human, Rat
- Purification
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the mid-protein of Human GDNF
- Isotype
- IgG
- Top Product
- Discover our top product GDNF Primary Antibody
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN5066760 was sufficient for detection of GDNF in 15 μg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- Alternative Name
- GDNF (GDNF Products)
- Synonyms
- gdnf antibody, GDNF antibody, AI385739 antibody, gdnfa antibody, hfb1-gdnf antibody, ATF1 antibody, ATF2 antibody, HFB1-GDNF antibody, HSCR3 antibody, glial cell derived neurotrophic factor antibody, glial cell derived neurotrophic factor a antibody, glial cell line derived neurotrophic factor antibody, glial cell derived neurotrophic factor L homeolog antibody, Gdnf antibody, gdnfa antibody, GDNF antibody, gdnf.L antibody
- Gene ID
- 2668
- NCBI Accession
- NP_000505
- UniProt
- P39905
- Pathways
- RTK Signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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