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WDR45 antibody (AA 312-322) (FITC)

WDR45 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal FITC
Catalog No. ABIN5066257
  • Target See all WDR45 Antibodies
    WDR45 (WD Repeat Domain 45 (WDR45))
    Binding Specificity
    • 10
    • 8
    • 7
    • 6
    • 3
    • 1
    AA 312-322
    Reactivity
    • 37
    • 3
    • 3
    Human
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WDR45 antibody is conjugated to FITC
    Application
    • 28
    • 14
    • 13
    • 10
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.,Detects ~40 kDa.
    Cross-Reactivity
    Human, Rat
    Purification
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)
    Isotype
    IgG
    Top Product
    Discover our top product WDR45 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:1000 dilution of ABIN5066257 was sufficient for detection of WIPI4 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    WDR45 (WD Repeat Domain 45 (WDR45))
    Alternative Name
    WDR45 (WDR45 Products)
    Synonyms
    MGC80694 antibody, NBIA4 antibody, NBIA5 antibody, WDRX1 antibody, WIPI-4 antibody, WIPI4 antibody, C79260 antibody, DXImx38e antibody, JM5 antibody, Sfc19 antibody, Wdrx1 antibody, zgc:56345 antibody, zgc:77017 antibody, WD repeat domain 45 S homeolog antibody, WD repeat domain 45 antibody, wdr45.S antibody, WDR45 antibody, Wdr45 antibody, wdr45 antibody
    Background
    WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.
    Gene ID
    11152
    NCBI Accession
    NP_001025067
    UniProt
    Q9Y484
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