UNC93B1 antibody (AA 300-597)

Catalog No. ABIN5027623

Product Details anti-UNC93B1 Antibody

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Binding Specificity: AA 300-597

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC93B1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 4-6 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for UNC93B1

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Alternative Name: UNC93B (UNC93B1 Products)

Synonyms: UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody

Background: Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.

Molecular Weight: 70 kDa

Gene ID: 81622

UniProt: Q9H1C4

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades