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RAX antibody (AA 100-313)

RAX Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5027505
  • Target See all RAX Antibodies
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Binding Specificity
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 100-313
    Reactivity
    • 16
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 11
    • 5
    Rabbit
    Clonality
    • 11
    • 5
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    This RAX antibody is un-conjugated
    Application
    • 14
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Protein A Chromatography
    Immunogen
    A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.
    Isotype
    IgG
    Top Product
    Discover our top product RAX Primary Antibody
  • Application Notes
    WB: 1-2 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    RAX (Retina and Anterior Neural Fold Homeobox (RAX))
    Alternative Name
    RAX (RAX Products)
    Synonyms
    MCOP3 antibody, RX antibody, 7530406A22Rik antibody, E130303K03Rik antibody, Rx antibody, ey-1 antibody, ey1 antibody, RAX antibody, rx antibody, rx1 antibody, Rx2A antibody, Xrax antibody, Xrx1 antibody, rax antibody, CG10052 antibody, DRx antibody, Dmel\\CG10052 antibody, Drx antibody, E97 antibody, PPH17 antibody, W60 antibody, bk50 antibody, drx antibody, wom antibody, Xrx2 antibody, rax-a antibody, rax1 antibody, rx1a antibody, rx2a antibody, retina and anterior neural fold homeobox antibody, Retinal Homeobox antibody, retina and anterior neural fold homeobox L homeolog antibody, retina and anterior neural fold homeobox S homeolog antibody, RAX antibody, Rax antibody, rax antibody, Rx antibody, rax.L antibody, rax.S antibody
    Background
    RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.
    Molecular Weight
    30 kDa
    Gene ID
    8575
    UniProt
    O75569
    Pathways
    Regulatory RNA Pathways
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