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IL1RL2 antibody (AA 1-203)
IL1RL2
Reactivity: Human
WB
Host: Mouse
Monoclonal
ABM47A2
unconjugated
Product Details anti-IL1RL2 Antibody
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Target
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IL1RL2
(Interleukin 1 Receptor-Like 2 (IL1RL2))
Binding Specificity
All epitopes for IL1RL2 antibodies
AA 1-203
Reactivity
All reactivities for IL1RL2 antibodies
Human
Host
All hosts for IL1RL2 antibodies
Mouse
Clonality
All clonalities for IL1RL2 antibodies
Monoclonal
Conjugate
All conjugates for IL1RL2 antibodies
This IL1RL2 antibody is un-conjugated
Application
All applications for IL1RL2 antibodies
Western Blotting (WB)
Purification
Protein G Chromatography
Immunogen
A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.
Clone
ABM47A2
Isotype
IgG2b
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Alternatives
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Application Details
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Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for IL1RL2
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Target
IL1RL2
(Interleukin 1 Receptor-Like 2 (IL1RL2))
Alternative Name
IL-36R (IL1RL2 Products )
Synonyms
IL-1Rrp2 antibody, IL-36R antibody, IL1R-rp2 antibody, IL1RRP2 antibody, AI481289 antibody, AW551444 antibody, interleukin 1 receptor like 2 antibody, interleukin 1 receptor-like 2 antibody, IL1RL2 antibody, Il1rl2 antibody
Background
IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.
Molecular Weight
69 kDa
Gene ID
8808
UniProt
Q9HB29
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