ZNRF3 antibody (AA 120-165) (AbBy Fluor® 750)
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- Target See all ZNRF3 Antibodies
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
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Binding Specificity
- AA 120-165
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZNRF3 antibody is conjugated to AbBy Fluor® 750
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ZNRF3
- Isotype
- IgG
- Top Product
- Discover our top product ZNRF3 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
- Alternative Name
- ZNRF3 (ZNRF3 Products)
- Synonyms
- BK747E2.3 antibody, RNF203 antibody, AA591877 antibody, BC019575 antibody, Gm1167 antibody, zinc and ring finger 3 antibody, Znrf3 antibody, ZNRF3 antibody
- Background
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Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133
Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
- Gene ID
- 84133
- UniProt
- Q9ULT6
- Pathways
- WNT Signaling
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