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ZNF536 antibody (N-Term)

ZNF536 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501163
  • Target See all ZNF536 Antibodies
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Binding Specificity
    • 8
    • 8
    • 6
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This ZNF536 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 13
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Affinity chromatography
    Immunogen
    16 amino acid peptide from near the amino terminus of human ZNF536
    Isotype
    IgG
    Top Product
    Discover our top product ZNF536 Primary Antibody
  • Application Notes
    ELISA. Western blot at 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Alternative Name
    ZNF536 (ZNF536 Products)
    Synonyms
    9630010P11Rik antibody, Znf536 antibody, mKIAA0390 antibody, RGD1563363 antibody, zinc finger protein 536 antibody, ZNF536 antibody, Zfp536 antibody
    Background
    ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and b-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.Synonyms: KIAA0390, Zinc finger protein 532, Zinc finger protein 532
    Gene ID
    9745
    NCBI Accession
    NP_055532
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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