H13 antibody (AA 251-350) (AbBy Fluor® 750)

Catalog No. ABIN5010954

Product Details anti-H13 Antibody (AbBy Fluor® 750)

Target: H13 (Histocompatibility 13 (H13))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H13 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Signal Peptide Peptidase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for H13

Target: H13 (Histocompatibility 13 (H13))

Alternative Name: SPP/ Signal Peptide Peptidase (H13 Products)

Synonyms: H13 antibody, IMP1 antibody, IMPAS antibody, IMPAS-1 antibody, MSTP086 antibody, PSENL3 antibody, PSL3 antibody, SPP antibody, SPPL1 antibody, dJ324O17.1 antibody, cb228 antibody, zgc:56660 antibody, zgc:86862 antibody, wu:fc11a06 antibody, h13 antibody, MGC68919 antibody, 1200006O09Rik antibody, 4930443L17Rik antibody, 5031424B04Rik antibody, AV020344 antibody, H-13 antibody, Hm13 antibody, Spp antibody, histocompatibility minor 13 antibody, histocompatibility (minor) 13 antibody, histocompatibility (minor) 13 L homeolog antibody, histocompatibility 13 antibody, HM13 antibody, hm13 antibody, hm13.L antibody, H13 antibody, Hm13 antibody

Background:

Synonyms: Histocompatibility minor 13, HM 13, HM13, HM13_HUMAN, IMP 1, IMP-1, IMP1, IMPAS, IMPAS-1, Intramembrane Protease 1, Intramembrane protease, Minor Histocompatibility 13, Minor histocompatibility antigen 13, Minor histocompatibility antigen H13, MSTP086, Presenilin like protein 3, Presenilin-like protein 3, PSENL 3, PSENL3, PSL 3, PSL3, Signal peptide peptidase, Signal peptide peptidase beta, SPP, dJ324O17.1, H13, hIMP1, hIMP1 protein.

Background: The endoplasmic reticulum exerts a quality control over newly synthesized proteins and a variety of components have been implicated in the specific recognition of aberrant or misfolded polypeptides. Signal peptide peptidase (SPP) catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. SPP is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides, and may play a role in graft rejection. It also may be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.

Gene ID: 207