SPOCK1 antibody (AbBy Fluor® 680)
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- Target See all SPOCK1 Antibodies
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPOCK1 antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1
- Isotype
- IgG
- Top Product
- Discover our top product SPOCK1 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- Alternative Name
- SPOCK1/ Testican 1 (SPOCK1 Products)
- Synonyms
- SPOCK antibody, TESTICAN antibody, TIC1 antibody, Spock antibody, Ticn1 antibody, testican antibody, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 antibody, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 antibody, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 antibody, SPOCK1 antibody, Spock1 antibody
- Background
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Synonyms: Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, SPOCK, Testican 1, Testican1, Testican-1, TIC1, TICN1, TICN1_HUMAN.
Background: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-1 is specifically expressed in the thalamus of the brain, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation. After a neural injury, such as a cerebral stroke, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions. Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover.
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