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SP6 antibody (AA 201-300) (AbBy Fluor® 680)

SP6 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 680
Catalog No. ABIN5010891
  • Target See all SP6 Antibodies
    SP6 (Sp6 Transcription Factor (SP6))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 47
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 46
    • 1
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SP6 antibody is conjugated to AbBy Fluor® 680
    Application
    • 35
    • 22
    • 12
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SP6
    Isotype
    IgG
    Top Product
    Discover our top product SP6 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SP6 (Sp6 Transcription Factor (SP6))
    Alternative Name
    SP6 (SP6 Products)
    Synonyms
    xsp6 antibody, MGC131081 antibody, EPFN antibody, EPIPROFIN antibody, KLF14 antibody, 1110025J03Rik antibody, AA591031 antibody, AI592962 antibody, Epfn antibody, Klf14 antibody, Sp6 transcription factor antibody, Sp5 transcription factor L homeolog antibody, trans-acting transcription factor 6 antibody, SP6 antibody, sp5.L antibody, Sp6 antibody
    Background

    Synonyms: MGC119665, Epfn, EPIPROFIN, KLF14, Krueppel-like factor 14, MGC119662, MGC119663, MGC119664, Sp6, Sp6 transcription factor, SP6_HUMAN, Transcription factor Sp6.

    Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96 % sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

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