SP6 antibody (AA 201-300) (AbBy Fluor® 680)
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- Target See all SP6 Antibodies
- SP6 (Sp6 Transcription Factor (SP6))
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Binding Specificity
- AA 201-300
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP6 antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SP6
- Isotype
- IgG
- Top Product
- Discover our top product SP6 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SP6 (Sp6 Transcription Factor (SP6))
- Alternative Name
- SP6 (SP6 Products)
- Synonyms
- xsp6 antibody, MGC131081 antibody, EPFN antibody, EPIPROFIN antibody, KLF14 antibody, 1110025J03Rik antibody, AA591031 antibody, AI592962 antibody, Epfn antibody, Klf14 antibody, Sp6 transcription factor antibody, Sp5 transcription factor L homeolog antibody, trans-acting transcription factor 6 antibody, SP6 antibody, sp5.L antibody, Sp6 antibody
- Background
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Synonyms: MGC119665, Epfn, EPIPROFIN, KLF14, Krueppel-like factor 14, MGC119662, MGC119663, MGC119664, Sp6, Sp6 transcription factor, SP6_HUMAN, Transcription factor Sp6.
Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Sp6, also known as EPFN, EPIPROFIN or KLF14, is a 376 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Expressed ubiquitously with higher expression in developing teeth, hair follicles and limb buds, Sp6 functions to bind GC-rich sequences and related GT and CACCC boxes, thereby promoting cellular proliferation. Human Sp6 shares 96 % sequence homology with its mouse counterpart, suggesting a conserved role between species. The gene encoding Sp6 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.
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