SLFN14 antibody (AbBy Fluor® 680)

Catalog No. ABIN5010680

Product Details anti-SLFN14 Antibody (AbBy Fluor® 680)

Target: SLFN14 (Schlafen Family Member 14 (SLFN14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLFN14 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLFN14

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLFN14

Target: SLFN14 (Schlafen Family Member 14 (SLFN14))

Alternative Name: SLFN14 (SLFN14 Products)

Synonyms: LRRGT00163 antibody, Gm20 antibody, Slfn14-ps antibody, schlafen family member 14 antibody, protein SLFN14 antibody, schlafen family member 11 antibody, schlafen 14 antibody, Slfn14 antibody, LOC491140 antibody, SLFN14 antibody, SLFN11 antibody, LOC100021434 antibody, LOC100358198 antibody

Background:

Synonyms: Schlafen family member 14, SLFN14, SLN14_HUMAN.

Background: Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

Gene ID: 342618

UniProt: P0C7P3