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KCNK18 antibody (Center)

KCNK18 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501034
  • Target See all KCNK18 Antibodies
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    Center
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNK18 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.
    Isotype
    IgG
    Top Product
    Discover our top product KCNK18 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Alternative Name
    KCNK18 (KCNK18 Products)
    Synonyms
    K2p18.1 antibody, MGR13 antibody, TRESK antibody, TRESK-2 antibody, TRESK2 antibody, TRIK antibody, Gm781 antibody, Tresk antibody, Tresk-2 antibody, Trik antibody, potassium two pore domain channel subfamily K member 18 antibody, potassium channel, subfamily K, member 18 antibody, KCNK18 antibody, Kcnk18 antibody
    Background
    TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.Synonyms: KCNK18, Potassium channel subfamily K member 18, TRESK, TRIK, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel
    Gene ID
    338567
    NCBI Accession
    NP_862823
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