EXOC3 antibody (AA 714-756) (AbBy Fluor® 750)

Catalog No. ABIN5010115

Product Details anti-EXOC3 Antibody (AbBy Fluor® 750)

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Binding Specificity: AA 714-756

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC3 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOC3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EXOC3

Target: EXOC3 (Exocyst Complex Component 3 (EXOC3))

Alternative Name: rSec6 (EXOC3 Products)

Background:

Synonyms: EXOC 3, EXOC3, Exocyst complex component 3, Exocyst complex component Sec 6, Exocyst complex component Sec6, rSec 6, Sec 6, Sec-6, Sec 6 homolog, Sec 6p, Sec6, SEC6 L1, SEC6 like 1, Sec6 protein, SEC6L1, Sec6p, EXOC3_HUMAN.

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Gene ID: 11336

UniProt: O60645

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis