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FNBP1L antibody (N-Term)

FNBP1L Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501004
  • Target See all FNBP1L Antibodies
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 46
    • 20
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 45
    • 1
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FNBP1L antibody is un-conjugated
    Application
    • 21
    • 18
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects FNBP1L at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    TOCA-1 antibody was raised against a 15 amino acid peptide near the amino terminus of the human TOCA-1.
    Isotype
    IgG
    Top Product
    Discover our top product FNBP1L Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Alternative Name
    FNBP1L (FNBP1L Products)
    Synonyms
    C1orf39 antibody, TOCA1 antibody, 2610318I01Rik antibody, AW548221 antibody, RGD1305386 antibody, Toca-1 antibody, zgc:100923 antibody, toca1 antibody, toca-1 antibody, MGC132162 antibody, fnbp1l antibody, formin binding protein 1 like antibody, formin binding protein 1-like antibody, formin binding protein 1 like L homeolog antibody, formin binding protein 1 like S homeolog antibody, FNBP1L antibody, Fnbp1l antibody, fnbp1l antibody, fnbp1l.L antibody, fnbp1l.S antibody
    Background
    Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells, its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.Synonyms: C1orf39, Formin-binding protein 1-like, TOCA1, Transducer of Cdc42-dependent actin assembly protein 1
    Gene ID
    54874
    NCBI Accession
    NP_001020119
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