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RNF180 antibody (AbBy Fluor® 750)

RNF180 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 750
Catalog No. ABIN5009944
  • Target See all RNF180 Antibodies
    RNF180 (Ring Finger Protein 180 (RNF180))
    Reactivity
    Human, Mouse, Rat
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF180 antibody is conjugated to AbBy Fluor® 750
    Application
    • 33
    • 14
    • 14
    • 12
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF180
    Isotype
    IgG
    Top Product
    Discover our top product RNF180 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RNF180 (Ring Finger Protein 180 (RNF180))
    Alternative Name
    RNF180 (RNF180 Products)
    Synonyms
    3110001E11Rik antibody, Rines antibody, ring finger protein 180 antibody, Rnf180 antibody, RNF180 antibody
    Background

    Synonyms: Rines, 3110001E11Rik, MGC120326, MGC120328, MGC188174, rCG_44674, Ring finger protein 180.

    Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF180 (ring finger protein 180), also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger. Expressed as three alternatively spliced isoforms, RNF180 is well conserved among vertebrates. RNF180 is expressed in brain, kidney, testis and uterus and localizes to the endoplasmic reticulum. RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. RNF180 is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

    Gene ID
    285671
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