Transmembrane Protein 70 (TMM70) (Center) antibody

Catalog No. ABIN500988

Product Details

Target: Transmembrane Protein 70 (TMM70)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TMEM70.

Purification: Peptide affinity chromatography

Immunogen: TMEM70 antibody was raised against a 14 amino acid peptide near the center of human TMEM70.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: Transmembrane Protein 70 (TMM70)

Alternative Name: TMEM70 (TMM70 Products)

Synonyms: MC5DN2 antibody, 1110020A09Rik antibody, 2210416J16Rik antibody, RGD1566224 antibody, transmembrane protein 70 antibody, TMEM70 antibody, Tmem70 antibody

Background: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.Synonyms: Transmembrane protein 70, mitochondrial

Gene ID: 54968

NCBI Accession: NP_060336