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TMEM38A antibody (C-Term)

TMEM38A Reactivity: Human, Rat, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500984
  • Target See all TMEM38A Antibodies
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Binding Specificity
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 8
    • 1
    Rabbit
    Clonality
    • 9
    Polyclonal
    Conjugate
    • 9
    This TMEM38A antibody is un-conjugated
    Application
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TMEM38A.
    Purification
    Peptide affinity chromatography
    Immunogen
    TMEM38A antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human TMEM38A.
    Isotype
    IgG
    Top Product
    Discover our top product TMEM38A Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TMEM38A (Transmembrane Protein 38A (TMEM38A))
    Alternative Name
    TMEM38A (TMEM38A Products)
    Synonyms
    zgc:77831 antibody, MGC75707 antibody, TMEM38A antibody, TRIC-A antibody, TRICA antibody, 1110001E17Rik antibody, AI413399 antibody, mg33a antibody, RGD1307901 antibody, Srp-27 antibody, transmembrane protein 38A antibody, transmembrane protein 38a antibody, transmembrane protein 38A L homeolog antibody, tmem38a antibody, CpipJ_CPIJ011791 antibody, CpipJ_CPIJ013655 antibody, TMEM38A antibody, Tmem38a antibody, tmem38a.L antibody
    Background
    TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.Synonyms: TRIC-A, TRICA, Transmembrane protein 38A, Trimeric intracellular cation channel type A
    Gene ID
    79041
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