RECK antibody (AA 801-900) (AbBy Fluor® 680)
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- Target See all RECK Antibodies
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Binding Specificity
- AA 801-900
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RECK antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RECK
- Isotype
- IgG
- Top Product
- Discover our top product RECK Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Alternative Name
- RECK (RECK Products)
- Synonyms
- ST15 antibody, St15 antibody, mRECK antibody, reversion inducing cysteine rich protein with kazal motifs antibody, reversion-inducing-cysteine-rich protein with kazal motifs antibody, RECK antibody, Reck antibody
- Background
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Synonyms: ST15, Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK
Background: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
- Gene ID
- 8434
- UniProt
- O95980
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