PPM1D antibody (AA 201-300) (AbBy Fluor® 680)
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- Target See all PPM1D Antibodies
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
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Binding Specificity
- AA 201-300
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPM1D antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PPM1D
- Isotype
- IgG
- Top Product
- Discover our top product PPM1D Primary Antibody
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- Application Notes
- IF(ICC) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
- Alternative Name
- PPM1D (PPM1D Products)
- Synonyms
- PP2C-DELTA antibody, WIP1 antibody, AV338790 antibody, Wip1 antibody, zgc:103518 antibody, ppm1d antibody, wu:fj44c08 antibody, zgc:55836 antibody, zgc:77316 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1D antibody, protein phosphatase 1D magnesium-dependent, delta isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1D antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Db antibody, protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Da antibody, PPM1D antibody, Ppm1d antibody, ppm1db antibody, ppm1d.L antibody, ppm1da antibody
- Background
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Synonyms: WIP1, PP2C-DELTA, Protein phosphatase 1D, Protein phosphatase 2C isoform delta, Protein phosphatase magnesium-dependent 1 delta, p53-induced protein phosphatase 1, PPM1D
Background: Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.
- Gene ID
- 8493
- UniProt
- O15297
- Pathways
- p53 Signaling, Cell Division Cycle
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