PLEC antibody (AA 4451-4550) (AbBy Fluor® 750)

Catalog No. ABIN5008964

Product Details anti-PLEC Antibody (AbBy Fluor® 750)

Target: PLEC (Plectin (PLEC))

Binding Specificity: AA 4451-4550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEC antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plectin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLEC

Target: PLEC (Plectin (PLEC))

Alternative Name: Plectin (PLEC Products)

Synonyms: EBS1 antibody, EBSO antibody, HD1 antibody, LGMD2Q antibody, PCN antibody, PLEC1 antibody, PLEC1b antibody, PLTN antibody, AA591047 antibody, AU042537 antibody, Plec1 antibody, Pcn antibody, Pltn antibody, IFAP300 antibody, Plectin-1 antibody, plectin antibody, plectin L homeolog antibody, LOC100481602 antibody, plec.L antibody, PLEC antibody, Plec antibody, LOC786966 antibody

Background:

Synonyms: EBS1, EBSO, HD1, Hemidesmosomal protein 1, PCN, PLEC1, PLEC1b, Plectin 1 plectin 1 intermediate filament binding protein 500 kDa, Plectin 6, PLTN.

Background: Plectin interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the crosslinking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.