RCHY1 antibody (AA 31-130) (AbBy Fluor® 750)
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- Target See all RCHY1 Antibodies
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
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Binding Specificity
- AA 31-130
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RCHY1 antibody is conjugated to AbBy Fluor® 750
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PIRH2
- Isotype
- IgG
- Top Product
- Discover our top product RCHY1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))
- Alternative Name
- PIRH2 (RCHY1 Products)
- Synonyms
- ARNIP antibody, CHIMP antibody, PIRH2 antibody, PRO1996 antibody, RNF199 antibody, ZNF363 antibody, Pirh2 antibody, Zfp363 antibody, Znf363 antibody, wu:fb37e07 antibody, zgc:101128 antibody, RCHY1 antibody, arnip antibody, chimp antibody, pirh2 antibody, harnip antibody, rnf199 antibody, znf363 antibody, pro1996 antibody, ring finger and CHY zinc finger domain containing 1 antibody, ring finger and CHY zinc finger domain containing 1 L homeolog antibody, RCHY1 antibody, Rchy1 antibody, rchy1 antibody, rchy1.L antibody
- Background
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Synonyms: ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996, RING finger and CHY zinc finger domain-containing protein 1, Androgen receptor N-terminal-interacting protein, CH-rich-interacting match with PLAG1, E3 ubiquitin-protein ligase Pirh2, RING finger protein 199, Zinc finger protein 363, p53-induced RING-H2 protein, hPirh2, RCHY1
Background: Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
- Gene ID
- 25898
- UniProt
- Q96PM5
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