PEG10 antibody (AA 301-400) (AbBy Fluor® 750)

Catalog No. ABIN5008656

Product Details anti-PEG10 Antibody (AbBy Fluor® 750)

Target: PEG10 (Paternally Expressed 10 (PEG10))

Binding Specificity: AA 301-400

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG10 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEG10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Alternative Name: PEG10 (PEG10 Products)

Synonyms: EDR antibody, HB-1 antibody, MEF3L antibody, Mar2 antibody, Mart2 antibody, RGAG3 antibody, AA407948 antibody, Edr antibody, MyEF-3 antibody, paternally expressed 10 antibody, PEG10 antibody, Peg10 antibody

Background:

Synonyms: Paternally expressed gene 10, MyEF 3, AA407948, Edr, Embryonal carcinoma dferentiation regulated, HB 1, HB1, KIAA1051, Mar2, Mart2, MEF3 like 1, MEF3L, MEF3L1, Paternally expressed 10, Paternally expressed gene 10 ORF1, PEG10 protein, Putative uncharacterized protein PEG10, Retrotransposon gag domain containing 3, RGAG3, PEG10_HUMAN, Retrotransposon-derived protein PEG10, Embryonal carcinoma dferentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, MEF3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, EDR.

Background: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].

Gene ID: 23089