PCYT2 antibody (AA 315-389) (AbBy Fluor® 680)
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- Target See all PCYT2 Antibodies
- PCYT2 (Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2))
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Binding Specificity
- AA 315-389
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCYT2 antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PCYT2
- Isotype
- IgG
- Top Product
- Discover our top product PCYT2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PCYT2 (Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2))
- Alternative Name
- PCYT2 (PCYT2 Products)
- Synonyms
- ET antibody, 1110033E03Rik antibody, ethanolamine-phosphate cytidylyltransferase antibody, putative ethanolamine-phosphate cytidylyltransferase antibody, Ethanolamine-phosphate cytidylyltransferase antibody, phosphate cytidylyltransferase 2, ethanolamine antibody, phosphate cytidylyltransferase 2, ethanolamine L homeolog antibody, Tc00.1047053511727.120 antibody, Tb11.01.5730 antibody, LINJ_32_0940 antibody, LOC5566800 antibody, LMJF_32_0890 antibody, EDI_013070 antibody, EDI_204270 antibody, CpipJ_CPIJ009320 antibody, Bm1_01855 antibody, pcy2 antibody, PCYT2 antibody, Pcyt2 antibody, pcyt2.L antibody
- Background
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Synonyms: CTP, phosphoethanolamine cytidylyltransferase, ET, Ethanolamine-phosphate cytidylyltransferase, Ethanolaminephosphate Cytidyltransferase, PCY2, PCY2_HUMAN, Pcyt2, Phosphate cytidylyltransferase 2 ethanolamine, Phosphorylethanolamine transferase.
Background: Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.
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