PARP16 antibody (AA 120-170) (AbBy Fluor® 750)
-
- Target See all PARP16 Antibodies
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
-
Binding Specificity
- AA 120-170
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PARP16 antibody is conjugated to AbBy Fluor® 750
-
Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PARP16
- Isotype
- IgG
- Top Product
- Discover our top product PARP16 Primary Antibody
-
-
- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
- Alternative Name
- PARP16 (PARP16 Products)
- Synonyms
- PARP16 antibody, zgc:77744 antibody, ARTD15 antibody, C15orf30 antibody, pART15 antibody, BC055447 antibody, C79952 antibody, PARP-16 antibody, LRRGT00109 antibody, RGD1306243 antibody, poly(ADP-ribose) polymerase family member 16 antibody, poly(ADP-ribose) polymerase family member 16 L homeolog antibody, poly (ADP-ribose) polymerase family, member 16 antibody, PARP16 antibody, parp16.L antibody, parp16 antibody, Parp16 antibody
- Background
-
Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.
Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.
- Gene ID
- 54956
- UniProt
- Q8N5Y8
-