STEAP2 antibody (C-Term)

Catalog No. ABIN500821

Product Details anti-STEAP2 Antibody

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects STEAP2 / STAMP1. It does not cross-react with other STEAP proteins.

Purification: Peptide affinity chromatography

Immunogen: STEAP2 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human STEAP2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Alternative Name: STEAP2 / STAMP1 (STEAP2 Products)

Synonyms: 4921538B17Rik antibody, AI930049 antibody, AW045895 antibody, IPCA-1 antibody, IPCA1 antibody, PCANAP1 antibody, STAMP1 antibody, STMP antibody, PUMPCn antibody, six transmembrane epithelial antigen of prostate 2 antibody, STEAP2 metalloreductase antibody, Steap2 antibody, STEAP2 antibody

Background: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.Synonyms: IPCA-1, IPCA1, Metalloreductase STEAP2, PCANAP1, PUMPCn, Prostate cancer-associated protein 1, Protein upregulated in metastatic prostate cancer, STEAP-2, STMP, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

Gene ID: 261729

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis