OxLDL antibody (AbBy Fluor® 750)

Catalog No. ABIN5008100

Product Details anti-OxLDL Antibody (AbBy Fluor® 750)

Target: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OxLDL antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Full length plasma protein (Human)

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OxLDL

Target: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Alternative Name: ox-LDL (OxLDL Products)

Background:

Synonyms: ox-LDL: Cu2SO4 oxidized low density lipoprotein, oxidized low density lipoprotein, Low density lipoprotein, MDA oxidized LDL, MDA oxidized low density lipoprotein.

Background: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.