C1orf63 antibody (AA 4-100) (AbBy Fluor® 750)
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- Target See all C1orf63 products
- C1orf63 (Chromosome 1 Open Reading Frame 63 (C1orf63))
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Binding Specificity
- AA 4-100
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This C1orf63 antibody is conjugated to AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NPD014
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- C1orf63 (Chromosome 1 Open Reading Frame 63 (C1orf63))
- Alternative Name
- NPD014 (C1orf63 Products)
- Synonyms
- NPD014 antibody, DJ465N24.2.1 antibody, RP3-465N24.4 antibody, DKFZp469M2120 antibody, arginine and serine rich protein 1 antibody, chromosome 1 open reading frame 63 antibody, RSRP1 antibody, C1orf63 antibody
- Background
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Synonyms: NPD014, C1orf63, DJ465N24.2.1, Arginine/serine-rich protein 1, RSRP1, HT033
Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf63 gene product has been provisionally designated C1orf63 pending further characterization.
- Gene ID
- 57035
- UniProt
- Q9BUV0
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