NOMO1 antibody (AA 701-800) (AbBy Fluor® 750)
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- Target See all NOMO1 Antibodies
- NOMO1 (NODAL Modulator 1 (NOMO1))
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Binding Specificity
- AA 701-800
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NOMO1 antibody is conjugated to AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NOMO1
- Isotype
- IgG
- Top Product
- Discover our top product NOMO1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NOMO1 (NODAL Modulator 1 (NOMO1))
- Alternative Name
- NOMO1 (NOMO1 Products)
- Synonyms
- Nomo antibody, PM5 antibody, D7Ertd156e antibody, pM5 antibody, RGD1305240 antibody, NOMO2 antibody, DKFZP459L1733 antibody, Nomo1 antibody, NODAL modulator 1 antibody, nodal modulator 1 antibody, NOMO1 antibody, Nomo1 antibody, LOC515570 antibody, LOC714226 antibody, LOC100025365 antibody, LOC100174326 antibody, LOC100408200 antibody, LOC100464689 antibody, LOC100544619 antibody, LOC100626015 antibody, LOC454345 antibody, LOC489992 antibody, LOC100713781 antibody
- Background
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Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.
Background: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
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