NIPAL3 antibody (AA 1-100) (AbBy Fluor® 680)

Catalog No. ABIN5007651

Product Details anti-NIPAL3 Antibody (AbBy Fluor® 680)

Target: NIPAL3 (NIPA-Like Domain Containing 3 (NIPAL3))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIPAL3 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIPAL3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NIPAL3

Target: NIPAL3 (NIPA-Like Domain Containing 3 (NIPAL3))

Alternative Name: NIPAL3 (NIPAL3 Products)

Synonyms: DJ462O23.2 antibody, NPAL3 antibody, 9130020G22Rik antibody, AI480660 antibody, Npal3 antibody, RGD1563439 antibody, NIPA like domain containing 3 antibody, NIPA-like domain containing 3 antibody, NIPAL3 antibody, Nipal3 antibody

Background:

Synonyms: NPAL3, NPAL-3, NIPA like domain containing 3, NIPA like protein 3, RGD1563439, RP23-332E2.5, RP3-462O23.3, NPAL3_HUMAN.

Background: NIPAL3 is a 406 amino acid multi-pass membrane protein that belongs to the NIPA family and exists as three alternatively spliced isoforms. The gene that encodes NPAL3 consists of approximately 57,229 bases and maps to human chromosome 1p36. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.