SLITRK3 antibody (C-Term)

Catalog No. ABIN500760

Product Details anti-SLITRK3 Antibody

Target: SLITRK3 (SLIT and NTRK-Like Family, Member 3 (SLITRK3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects SLITRK3 at center. It is predicted to have no cross-reactivity to other Slitrk proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: Slitrk3 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Slitrk3.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for SLITRK3

Target: SLITRK3 (SLIT and NTRK-Like Family, Member 3 (SLITRK3))

Alternative Name: SLITRK3 (SLITRK3 Products)

Synonyms: SLIT and NTRK-like family, member 3 antibody, SLIT and NTRK like family member 3 antibody, SKI like proto-oncogene antibody, Slitrk3 antibody, SLITRK3 antibody, slitrk3 antibody, SKIL antibody

Background: SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.Synonyms: KIAA0848, SLIT and NTRK-like protein 3

Gene ID: 22865

UniProt: O94933