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SLITRK2 antibody (Middle Region)

SLITRK2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500756
  • Target See all SLITRK2 Antibodies
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 48
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    Human, Mouse, Rat
    Host
    • 48
    Rabbit
    Clonality
    • 48
    Polyclonal
    Conjugate
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLITRK2 antibody is un-conjugated
    Application
    • 43
    • 26
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects SLITRK2 at center. It is predicted to have no cross-reactivity to other Slitrk proteins.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    Slitrk2 antibody was raised against a 16 amino acid peptide from near the center of human Slitrk2.
    Isotype
    IgG
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  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    Alternative Name
    SLITRK2 (SLITRK2 Products)
    Synonyms
    slitrk2 antibody, CXorf2 antibody, SLITL1 antibody, A930040J07 antibody, RGD1561361 antibody, SLIT and NTRK-like family, member 2 antibody, SLIT and NTRK like family member 2 antibody, SLITRK2 antibody, slitrk2 antibody, Slitrk2 antibody
    Background
    SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.Synonyms: CXorf2, KIAA1854, SLIT and NTRK-like protein 2, SLITL1
    Gene ID
    84631
    UniProt
    Q9H156
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