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MEGF10 antibody (AA 55-150) (AbBy Fluor® 750)

MEGF10 Reactivity: Mouse IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 750
Catalog No. ABIN5006698
  • Target See all MEGF10 Antibodies
    MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))
    Binding Specificity
    • 14
    • 4
    • 3
    • 1
    AA 55-150
    Reactivity
    • 16
    • 10
    • 2
    Mouse
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MEGF10 antibody is conjugated to AbBy Fluor® 750
    Application
    • 12
    • 12
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MEGF10
    Isotype
    IgG
    Top Product
    Discover our top product MEGF10 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MEGF10 (Multiple EGF-Like-Domains 10 (MEGF10))
    Alternative Name
    MEGF10 (MEGF10 Products)
    Synonyms
    EMARDD antibody, 3000002B06Rik antibody, Gm331 antibody, multiple EGF-like domains 10 antibody, multiple EGF like domains 10 antibody, multiple EGF-like-domains 10 antibody, Megf10 antibody, MEGF10 antibody
    Background

    Synonyms: MEG10_HUMAN, MEGF protein, megf10, Multiple EGF-like domains protein 10, multiple EGF-like-domains 10, Multiple epidermal growth factor-like domains 10, Multiple epidermal growth factor-like domains protein 10.

    Background: MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.

    Gene ID
    84466
    Pathways
    Regulation of Muscle Cell Differentiation
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