DLGAP2
Reactivity: Human, Rat
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 647
Application Notes
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
DLGAP2
(Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
PSD-95 antibody, DAP2 antibody, SAPAP2 antibody, 6430596N04Rik antibody, Sapap2 antibody, DLG associated protein 2 antibody, disks large-associated protein 2 antibody, discs, large (Drosophila) homolog-associated protein 2a antibody, discs, large (Drosophila) homolog-associated protein 2 antibody, DLGAP2 antibody, LOC463960 antibody, dlgap2a antibody, LOC100447448 antibody, Dlgap2 antibody
Background
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP2 are known to exist.Synonyms: DAP-2, DAP2, Disks large-associated protein 2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2