DLGAP2 antibody (Center)

Catalog No. ABIN500654

Product Details anti-DLGAP2 Antibody

Target: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Binding Specificity: Center

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLGAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects SAPAP2. It will not cross-react with other SAPAP proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: SAPAP2 antibody was raised against a 16 amino acid peptide from near the center of human SAPAP2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for DLGAP2

Target: DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))

Alternative Name: DLGAP2 (DLGAP2 Products)

Synonyms: PSD-95 antibody, DAP2 antibody, SAPAP2 antibody, 6430596N04Rik antibody, Sapap2 antibody, DLG associated protein 2 antibody, disks large-associated protein 2 antibody, discs, large (Drosophila) homolog-associated protein 2a antibody, discs, large (Drosophila) homolog-associated protein 2 antibody, DLGAP2 antibody, LOC463960 antibody, dlgap2a antibody, LOC100447448 antibody, Dlgap2 antibody

Background: SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP2 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP2 are known to exist.Synonyms: DAP-2, DAP2, Disks large-associated protein 2, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2

Gene ID: 9228

UniProt: Q9P1A6