MAP1B antibody (AA 451-550) (AbBy Fluor® 680)

Catalog No. ABIN5006496

Product Details anti-MAP1B Antibody (AbBy Fluor® 680)

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Binding Specificity: AA 451-550

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1B antibody is conjugated to AbBy Fluor® 680

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAP1B

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAP1B

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Alternative Name: MAP1B (MAP1B Products)

Synonyms: FUTSCH antibody, MAP5 antibody, Mtap1b antibody, A230055D22 antibody, AI843217 antibody, LC1 antibody, Mtap-5 antibody, Mtap5 antibody, microtubule associated protein 1B antibody, microtubule-associated protein 1B antibody, MAP1B antibody, Map1b antibody

Background:

Synonyms: MAP5, FUTSCH, PPP1R102, Microtubule-associated protein 1B, MAP-1B, MAP1B

Background: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

Gene ID: 4131

UniProt: P46821

Pathways: Microtubule Dynamics, Regulation of Cell Size