LRPPRC antibody (AbBy Fluor® 680)

Catalog No. ABIN5006297

Product Details anti-LRPPRC Antibody (AbBy Fluor® 680)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP130

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: LRP130 (LRPPRC Products)

Synonyms: CLONE-23970 antibody, GP130 antibody, LRP130 antibody, LSFC antibody, Lrp157 antibody, 3110001K13Rik antibody, C76645 antibody, Gp130 antibody, Lrp130 antibody, Lsfc antibody, leucine rich pentatricopeptide repeat containing antibody, leucine-rich pentatricopeptide repeat containing antibody, leucine-rich PPR-motif containing antibody, LRPPRC antibody, Lrpprc antibody

Background:

Synonyms: LRPPRC, 130 kDa leucine-rich protein, GP130, Leucine-rich PPR-mot containing protein, LRP 130, LPPRC_HUMAN.

Background: Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.