RHBDD2 antibody (Center)

Catalog No. ABIN500591

Product Details anti-RHBDD2 Antibody

Target: RHBDD2 (Rhomboid Domain Containing 2 (RHBDD2))

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHBDD2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide afffinity chromatography

Immunogen: RHBDD2 antibody was raised against an 18 amino acid peptide from near the center of human RHBDD2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

References for anti-RHBDD2 antibody (ABIN500591)

Ferretti, Canzoneri, Barbeito, Croce, Abba, Lacunza: "Spatiotemporal expression of Rhomboid domain containing 2 (Rhbdd2) during rat development." in: Acta histochemica, Vol. 117, Issue 7, pp. 635-41, (2016) (PubMed).

Canzoneri, Lacunza, Isla Larrain, Croce, Abba: "Rhomboid family gene expression profiling in breast normal tissue and tumor samples." in: Tumour biology, Vol. 35, Issue 2, pp. 1451-8, (2014) (PubMed).

Target Details for RHBDD2

Target: RHBDD2 (Rhomboid Domain Containing 2 (RHBDD2))

Alternative Name: RHBDD2 (RHBDD2 Products)

Synonyms: NPD007 antibody, RHBDL7 antibody, 0610011L13Rik antibody, AI480532 antibody, Rhbdl7 antibody, Usmg1 antibody, rhomboid domain containing 2 antibody, RHBDD2 antibody, Rhbdd2 antibody

Background: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. Little is known about the role of RHBDD2. Its overexpression in breast carcinoma appears to be an indicator of poor prognosis and may play a role in breast cancer progression. The related proteins RHBDD1 and RHBDD3 are both involved in the regulation of apoptosis, suggesting that RHBDD2 may also be involved in the modulation of apoptotic activity.Synonyms: RHBDL7, Rhomboid domain-containing protein 2

Gene ID: 57414

NCBI Accession: NP_001035546

UniProt: Q6NTF9