PPAPDC1A antibody (C-Term)

Catalog No. ABIN500527

Product Details anti-PPAPDC1A Antibody

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Binding Specificity: C-Term

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAPDC1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: PPAPDC1A antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PPAPDC1A.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for PPAPDC1A

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Alternative Name: PPAPDC1A (PPAPDC1A Products)

Synonyms: PPAPDC1A antibody, PPAPDC1 antibody, DPPL2 antibody, C030048B12Rik antibody, Gm1090 antibody, RGD1306289 antibody, phospholipid phosphatase 4 antibody, phospholipid phosphatase 4 L homeolog antibody, PLPP4 antibody, plpp4.L antibody, Plpp4 antibody

Background: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.Synonyms: DPPL2, PPAPDC1, Phosphatidate phosphatase PPAPDC1A, Phosphatidic acid phosphatase type 2 domain-containing protein 1A

Gene ID: 196051

NCBI Accession: NP_001025230

UniProt: Q5VZY2