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ANP32E antibody (C-Term)

ANP32E Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500487
  • Target See all ANP32E Antibodies
    ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANP32E antibody is un-conjugated
    Application
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ANP32E / PHAP III. It has no cross-reaction to PHAP I and PHAP I2a.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    ANP32E antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human ANP32E / PHAP III.
    Isotype
    IgG
    Top Product
    Discover our top product ANP32E Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 to 2 μg/mL, a band at approximately 35 kDa can be detected. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))
    Alternative Name
    ANP32E (ANP32E Products)
    Synonyms
    LANP-L antibody, LANPL antibody, ANP32E antibody, wu:fb22e03 antibody, wu:fc04c12 antibody, wu:fc19a08 antibody, wu:fc79f04 antibody, wu:fi39c10 antibody, zgc:65995 antibody, zgc:85827 antibody, DKFZp459A0729 antibody, 2810018A15Rik antibody, AI047746 antibody, AI326868 antibody, CPD1 antibody, mLANP-L antibody, MGC180507 antibody, acidic nuclear phosphoprotein 32 family member E antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member E antibody, acidic nuclear phosphoprotein 32 family member E L homeolog antibody, acidic leucine-rich nuclear phosphoprotein 32 family member E-like antibody, ANP32E antibody, anp32e antibody, Anp32e antibody, anp32e.L antibody, LOC100349957 antibody, LOC100355663 antibody
    Background
    Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member E, LANP-L, LANP-like protein, LANPL, PHAP III
    Gene ID
    81611
    NCBI Accession
    NP_112182
    UniProt
    Q9BTT0
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