PCDH18 antibody (N-Term)
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- Target See all PCDH18 Antibodies
- PCDH18 (Protocadherin 18 (PCDH18))
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Binding Specificity
- N-Term
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Reactivity
- Mouse, Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCDH18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects PCDH18. It is predicted to not cross-react with PCDH12.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogen
- PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.
- Isotype
- IgG
- Top Product
- Discover our top product PCDH18 Primary Antibody
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- Application Notes
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- PCDH18 (Protocadherin 18 (PCDH18))
- Alternative Name
- PCDH18 (PCDH18 Products)
- Synonyms
- PCDH68L antibody, 3110038E07Rik antibody, BB095589 antibody, protocadherin 18 antibody, PCDH18 antibody, Pcdh18 antibody
- Background
- Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs. Tissue screening revealed PCDH18 broad expression in tissues such as brain, liver, heart, kidney, lung, and trachea. PCDH18 expression is also temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development. PCDH18 was also found to be expressed in the developing zebrafish neural tube and central nervous system, lending support to the hypothesis that PCDH18 may play a role during brain development. At least three isoforms of PCDH18 are known to exist.Synonyms: KIAA1562, Protocadherin 18, Protocadherin-18
- Gene ID
- 54510
- NCBI Accession
- NP_061908
- UniProt
- Q9HCL0
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