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ORAI2 antibody (C-Term)

ORAI2 Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500423
  • Target See all ORAI2 Antibodies
    ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 22
    • 18
    • 16
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ORAI2 antibody is un-conjugated
    Application
    • 22
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ORAI2 at C-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI3.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Peptide affinity chromatography
    Immunogen
    ORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.
    Isotype
    IgG
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    Discover our top product ORAI2 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))
    Alternative Name
    ORAI2 (ORAI2 Products)
    Synonyms
    C7orf19 antibody, CBCIP2 antibody, MEM142B antibody, TMEM142B antibody, A730041O15Rik antibody, Tmem142b antibody, RGD1310213 antibody, ORAI2 antibody, orai-1 antibody, orai1 antibody, tmem142a antibody, tmem142b antibody, LOC100230993 antibody, ORAI calcium release-activated calcium modulator 2 antibody, ORAI calcium release-activated calcium modulator 2 S homeolog antibody, ORAI2 antibody, Orai2 antibody, orai2.S antibody, orai2 antibody
    Background
    Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.Synonyms: C7orf19, CAP-binding protein complex-interacting protein 2, CBCIP2, Protein orai-2, TMEM142B, Transmembrane protein 142B
    Gene ID
    80228
    UniProt
    Q96SN7
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