NUP155 antibody (C-Term)

Catalog No. ABIN500397

Product Details anti-NUP155 Antibody

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP155 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects NUP155 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: NUP155 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human NUP155.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for NUP155

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Alternative Name: NUP155 (NUP155 Products)

Synonyms: F10B6.25 antibody, F10B6_25 antibody, nucleoporin 155 antibody, DDBDRAFT_0189286 antibody, DDBDRAFT_0235243 antibody, DDB_0189286 antibody, DDB_0235243 antibody, D930027M19Rik antibody, mKIAA0791 antibody, zgc:55435 antibody, N155 antibody, nucleoporin 155 antibody, nucleoporin 155kDa antibody, nuclear pore protein antibody, nucleoporin 155kDa L homeolog antibody, NUP155 antibody, nup155 antibody, Nup155 antibody, nup155.L antibody

Background: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.Synonyms: 155 kDa nucleoporin, KIAA0791, Nuclear pore complex protein Nup155, Nucleoporin Nup155

Gene ID: 9631

NCBI Accession: NP_705618

UniProt: O75694

Pathways: Protein targeting to Nucleus