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GOT1L1 antibody (AA 201-300) (AbBy Fluor® 680)

GOT1L1 Reactivity: Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 680
Catalog No. ABIN5003783
  • Target See all GOT1L1 products
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    AA 201-300
    Reactivity
    • 29
    • 14
    • 3
    Mouse, Rat
    Host
    • 29
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GOT1L1 antibody is conjugated to AbBy Fluor® 680
    Application
    • 29
    • 15
    • 14
    • 13
    • 12
    • 12
    • 6
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GOT1L1
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    Alternative Name
    GOT1L1 (GOT1L1 Products)
    Synonyms
    1700083M11Rik antibody, RGD1307172 antibody, glutamic-oxaloacetic transaminase 1 like 1 antibody, glutamic-oxaloacetic transaminase 1-like 1 antibody, GOT1L1 antibody, Got1l1 antibody
    Background

    Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.

    Background: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

    Gene ID
    137362
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