GMEB1 antibody (AA 301-400) (AbBy Fluor® 680)
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- Target See all GMEB1 Antibodies
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
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Binding Specificity
- AA 301-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GMEB1 antibody is conjugated to AbBy Fluor® 680
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GMEB1
- Isotype
- IgG
- Top Product
- Discover our top product GMEB1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
- Alternative Name
- GMEB1 (GMEB1 Products)
- Synonyms
- MGC81052 antibody, GMEB1 antibody, si:ch211-245h7.5 antibody, pif96 antibody, p96pif antibody, MGC147529 antibody, P96PIF antibody, PIF96 antibody, 1110050A04Rik antibody, AI256615 antibody, AI481278 antibody, RGD1563208 antibody, glucocorticoid modulatory element binding protein 1 S homeolog antibody, glucocorticoid modulatory element binding protein 1 antibody, gmeb1.S antibody, GMEB1 antibody, gmeb1 antibody, Gmeb1 antibody
- Background
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Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.
Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
- Gene ID
- 10691
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